Selected Publications

Organoids

• F Ye, E Kang, C Yu, X Qian, F Jacob, C Yu, M Mao, RYC Poon, J Kim, et al. DISC1 regulates neurogenesis via modulating kinetochore attachment of Ndel1/Nde1 during mitosis. Neuron. 2017. Link
• X Qian, HN Nguyen, MM Song, C Hadiono, SC Ogden, C Hammack et al. Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure. Cell. 2016. Link

Neurogenesis

• DA Berg, Y Su,D Jimenez-Cyrus, A Patel, N Huang, D Morizet, et al. A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis. 2019. Cell, April 28. Link
• DA Berg, AM Bond, G Ming, H Song. Radial glial cells in the adult dentate gyrus: what are they and where do they come from? F1000Research. 2018 Link
• J Shin, DA Berg, Y Zhu, JY Shin, J Song, MA Bonaguidi, G Enikolopov et al. Single-cell RNA-seq with waterfall reveals molecular cascades underlying adult neurogenesis. Cell Stem Cell. 2015. Link
• DA Berg, KJ Yoon, B Will, AY Xiao, NS Kim, KM Christian, H Song, G Ming. Tbr2-expressing intermediate progenitor cells in the adult mouse hippocampus are unipotent neuronal precursors with limited amplification capacity under homeostasis. Frontiers in Biology 2015. Link
• MH Jang, MA Bonaguidi, Y Kitabatake, J Sun, J Song, E Kang et al. Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell Stem Cell 2013. Link
• DA Berg, M Kirkham, H Wang, J Frisén, A Simon. Dopamine controls neurogenesis in the adult salamander midbrain in homeostasis and during regeneration of dopamine neurons. Cell Stem Cell. 2011. Link
• DA Berg, M Kirkham, A Beljajeva, D Knapp, B Habermann, et al. Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain. Development. 2010. Link

Psyciatric disorders

• E Kang, J Song, Y Lin, J Park, JH Lee, Q Hussani, Y Gu, S Ge et al. Interplay between a mental disorder risk gene and developmental polarity switch of GABA action leads to excitation-inhibition imbalance. Cell Reports 2019. Link
• E Kang, Z Wen, H Song, KM Christian, G Ming. Adult neurogenesis and psychiatric disorders. Cold Spring Harbor perspectives in biology. 2018;360(6386),eaaq1392. Link
• H Zhang, E Kang, Y Wang, C Yang, H Yu, Q Wang, Z Chen, C Zhang, et al. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nature Communications. 2016. Link
• H Lee, E Kang, D GoodSmith, DY Yoon, H Song, JJ Knierim et al. DISC1-mediated dysregulation of adult hippocampal neurogenesis in rats. Frontiers in systems Neuroscience. 2015. Link
• H Zhang, E Kang, Y Wang, C Yang, H Yu, Q Wang, Z Chen, C Zhang, et al. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nature Communications. 2016. Link

Neurotoxicity

• J Neudecker, Xu, Thomas, Penberthy, Kang, Berg, O’Meara, Brambrink, Mintz. An Update on Preclinical Research in Anesthetic-Induced Developmental Neurotoxicity in Nonhuman Primate and Rodent Models Journal of Neurosurgical Anesthesiology (35), 104-113 2023. Link
• J Xu, E Kang, CD Mintz. Anesthetics disrupt brain development via actions on the mTOR pathway Communicative & integrative biology 11 (2), 1-4 2018. Link
• E Kang, D Jiang, KY Ryu, S Lim, Kwak M, CD Grey, M Xu, JH Choi, S Junn, J Kim, J Xu, M Scaefer, RA Johns, H Song, GL Ming, CD Mintz. Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway PLoS biology 15 (7) 2017. Link
• E Kang, DA Berg, O Furmanski, WM Jackson, YK Ryu, CD Gray, CD Mintz. Neurogenesis and developmental anesthetic neurotoxicity Neurotoxicology and teratology 60, 33-39 2017. Link
• E M Kwak, S Lim, E Kang, O Furmanski, H Song, YK Ryu, CD Mintz. Effects of neonatal hypoxic-ischemic injury and hypothermic neuroprotection on neural progenitor cells in the mouse hippocampus. Developmental Neuroscience 2015. Link